Contrave

About this medicine

Composition of the medicine

Contrave contains two key active ingredients that ensure its effectiveness. Naltrexone and bupropion work in tandem to achieve weight loss goals. Naltrexone is commonly used to treat alcohol and drug addiction, while bupropion is known as an antidepressant and smoking cessation aid.

• Naltrexone, an opioid receptor blocker, helps control food cravings and reduces dependence on high-calorie, high-fat foods.
• Bupropion increases dopamine levels, improving mood and supporting motivation for physical activity and diet.

These two components work together to offer a comprehensive weight management solution by addressing the psycho-emotional factors that can interfere with successful weight loss.

Usage and dosage

Contrave should be taken orally with a small amount of water. It is important to follow your doctors instructions or the package directions. Do not break, chew, or crush the tablets; swallow them whole.

1. Take this medication once daily unless otherwise directed by your doctor.
2. Contrave can be taken with or without food, but avoid fatty meals, as they may increase the risk of seizures.
3. Do not increase the frequency of dosing or stop taking the medication without your doctors advice.

Proper use of Contrave is important to achieve the desired results and minimize potential side effects.

How does this medicine work?

Contrave works by influencing the brain in several ways. Its primary goal is to reduce appetite and prevent cravings for high-calorie foods, making it easier to adhere to a low-calorie diet. This is achieved through naltrexone, which blocks certain receptors in the brain. These receptors typically stimulate food cravings and create addiction, hindering weight loss.

At the same time, bupropion increases dopamine production, which improves mood and increases motivation. This approach is important for maintaining long-term dieting and regular exercise. This combination allows patients to feel more energetic and resilient to stress, ultimately contributing to successful weight loss.

Indications for use

Contrave has a number of indications that make it suitable for specific patient groups. It is used in adults seeking weight loss and maintenance under certain conditions.

• Treatment of obesity in adults with a body mass index (BMI) over 30.
• Overweight patients (BMI 27 or higher) with comorbidities such as hypertension or type 2 diabetes.
• Used as an adjunct to a reduced-calorie diet and increased physical activity.

These indications allow Contrave to be used for weight management in people whose health may be compromised by excess weight.

Contraindications for use

Contrave has a number of contraindications that should be considered before use. These restrictions help prevent potential complications and adverse reactions.

• Allergy to any of the drugs components, such as bupropion or naltrexone.
• Pregnancy or breastfeeding, as weight loss during this period may harm the mother or baby.
• History of seizure disorders, as Contrave may increase the risk of seizures.
• Liver or kidney failure, as the drug may increase the stress on these organs.
• Consumption of large amounts of alcohol, as this may cause adverse interactions.

Adherence to these contraindications is important for the safe and effective use of the drug.

Side effects

Like any medication, Contrave can cause side effects. While not everyone experiences them, being aware of them can help you make informed decisions about your treatment.

• Sleep disturbances, such as insomnia, may occur during the first weeks of treatment.
• Headaches and dizziness may occur periodically throughout treatment.
• Nausea or stomach upset most often occur at the beginning of treatment and usually resolve on their own.
• Increased risk of seizures, especially when taken with alcohol or fatty foods.
• Behavioral changes, such as increased irritability or anxiety.

If any serious symptoms occur, it is recommended to consult your doctor immediately.